Investigating how immune cells interact with tumor-associated macrophages in lung cancer.
Cancer-Cell and T-cell Dependent Regulation of Tumor Associated Macrophages
This study is looking at how the immune system, especially certain immune cells, interacts with lung cancer to find better ways to treat it, and it could help patients by leading to new and improved therapies.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10683723 on NIH RePORTER |
What this research studies
This research focuses on understanding the immune responses against lung cancer, particularly how T-cells and cancer cells regulate tumor-associated macrophages. The principal investigator, with a strong background in immunology and oncology, aims to develop new techniques for analyzing immune interactions in lung adenocarcinoma. The project includes training in advanced molecular profiling and computational biology, which will enhance the understanding of lung cancer immunobiology and potential therapies. Patients may benefit from insights gained through this research that could lead to improved immunotherapy strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with lung cancer, particularly those with non-small cell lung carcinoma.
Not a fit: Patients with cancers other than lung cancer or those not eligible for immunotherapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective immunotherapies for lung cancer patients.
How similar studies have performed: Previous research has shown promising results in understanding immune responses in cancer, indicating that this approach has potential for success.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Ward, Jeffrey P — Washington University
- Study coordinator: Ward, Jeffrey P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.