Investigating how immune cells help heal skin injuries caused by chemical agents.
Official title: The Role of Macrophages in Vesicant Skin Injury and Repair
Funded at University of Illinois at Chicago · NIH-11054606 · Data updated 2026-11-12
This study is looking at how certain immune cells help heal skin injuries caused by harmful chemicals, and it aims to find new ways to improve recovery for people affected by these types of injuries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project start | June 13, 2023 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $236,745 |
| NIH project number | 5R34AR081456-03 |
| Project ID | NIH-11054606 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced skin injuries from chemical agents or those with conditions that lead to similar skin damage.
✕Less likely to help
Patients with skin injuries not related to chemical exposure or those with non-inflammatory skin conditions may not benefit from this research.
What this research studies
This research focuses on understanding the role of macrophages, a type of immune cell, in the healing process of skin injuries caused by chemical warfare agents like mustards and arsenicals. By using advanced single-cell techniques, the researchers aim to explore how these immune cells respond to skin damage and contribute to inflammation and healing. The study will involve experiments with specific chemical agents to gather data that could inform future treatments for skin injuries. Patients may benefit from insights gained about the healing process and potential therapies that could enhance recovery.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for skin injuries caused by chemical exposure, enhancing healing and recovery for affected patients.
How similar studies have gone: Previous research has shown promise in understanding immune responses to skin injuries, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Illinois at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Koh, Timothy J — University of Illinois at Chicago
- Study coordinator: Koh, Timothy J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.