Investigating how immune cells affect lung problems after COVID-19
Official title: Immune Programs and Related T Cell Mechanisms of Pulmonary Complications After COVID-19 Illness
Funded at University of Virginia · NIH-10886167 · Data updated 2026-11-12
This study is looking at how certain immune cells called T cells might be causing lung problems in people who have recovered from severe COVID-19, and it's for anyone who wants to understand more about their recovery and what might help improve their lung health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $410,000 |
| NIH project number | 1R56AI178669-01 |
| Project ID | NIH-10886167 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced severe COVID-19 illness and are suffering from persistent lung complications.
✕Less likely to help
Patients who have not had severe COVID-19 or do not exhibit any pulmonary complications may not benefit from this research.
What this research studies
This research focuses on understanding the role of T cells in causing lung complications in patients who have recovered from severe COVID-19. By using advanced techniques like single-cell analysis and machine learning, the study aims to identify specific immune cell populations in the blood that may contribute to ongoing lung issues. The researchers will analyze a well-defined group of COVID-19 patients to uncover the cellular and molecular mechanisms behind these complications, potentially leading to better treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of lung damage in COVID-19 survivors.
How similar studies have gone: Other research has shown promise in understanding immune responses in COVID-19, but this approach is particularly innovative and tailored to the complexities of pulmonary complications.
Where this research is happening
-
University of Virginia
Charlottesville, United States Active
Researchers
- Principal investigator: Woodfolk, Judith a — University of Virginia
- Study coordinator: Woodfolk, Judith a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.