Investigating how immune activation and gut health affect health issues in people with HIV
Effects of Targeting Immune Activation and Intestinal Barrier on Comorbidities in People with HIV
This study is looking at how the immune system and gut health are connected in people with HIV, to better understand and find ways to prevent common health issues like heart disease, obesity, and diabetes, even for those on treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10924678 on NIH RePORTER |
What this research studies
This research focuses on understanding the link between immune system activation and the health of the intestinal barrier in individuals living with HIV. It aims to explore how these factors contribute to common health problems such as cardiovascular disease, obesity, and diabetes, even in patients receiving effective antiretroviral therapy. By collaborating with a team of experts across various medical fields, the project seeks to identify potential prevention and treatment strategies for these comorbidities. The research will involve patient-oriented approaches to gather insights and develop interventions that could improve health outcomes for this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are living with HIV and experiencing comorbidities such as cardiovascular disease or metabolic disorders.
Not a fit: Patients who are not living with HIV or who do not have related comorbidities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management and treatment options for health issues faced by people living with HIV.
How similar studies have performed: Previous research has shown promising results in addressing similar health issues in HIV populations, indicating that this approach has potential for success.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Lo, Janet — Massachusetts General Hospital
- Study coordinator: Lo, Janet
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.