Investigating how hydrogen sulfide affects blood vessel aging
Cystathionine Gamma Lyase (CSE) and Hydrogen Sulfide Regulation of Vascular Aging
['FUNDING_OTHER'] · LOUISIANA STATE UNIV HSC SHREVEPORT · NIH-10879024
This study is looking at how a substance called CSE and a gas called hydrogen sulfide affect the health of blood vessels as we get older, with the hope of finding new ways to help older adults have healthier hearts and blood vessels.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LOUISIANA STATE UNIV HSC SHREVEPORT (nih funded) |
| Locations | 1 site (SHREVEPORT, UNITED STATES) |
| Trial ID | NIH-10879024 on ClinicalTrials.gov |
What this research studies
This research explores the role of cystathionine gamma lyase (CSE) and hydrogen sulfide (H2S) in the aging of blood vessels, which is crucial for understanding cardiovascular diseases. The study aims to uncover how deficiencies in CSE and H2S contribute to vascular dysfunction as people age. By examining the molecular mechanisms involved, the research seeks to identify potential targets for improving vascular health in older adults. Patients may benefit from insights that could lead to new treatments for age-related cardiovascular issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing cardiovascular issues or those at risk due to aging.
Not a fit: Patients with cardiovascular conditions unrelated to aging or those who are not elderly may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating cardiovascular diseases associated with aging.
How similar studies have performed: While the specific role of CSE and H2S in vascular aging is still being explored, related research has shown promising results in understanding vascular health and aging.
Where this research is happening
SHREVEPORT, UNITED STATES
- LOUISIANA STATE UNIV HSC SHREVEPORT — SHREVEPORT, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KOLLURU, GOPI K — LOUISIANA STATE UNIV HSC SHREVEPORT
- Study coordinator: KOLLURU, GOPI K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia