Investigating how hyaluronic acid affects endometriosis

The role of hyaluronic acid and its receptors in the pathogenesis of endometriosis

['FUNDING_OTHER'] · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · NIH-10894459

This study is looking at how a substance called hyaluronic acid affects the growth of endometriosis, a condition that many women experience, and it’s exploring how a specific drug might help in treating it by stopping the production of hyaluronic acid.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF TEXAS HLTH SCIENCE CENTER (nih funded)
Locations1 site (SAN ANTONIO, UNITED STATES)
Trial IDNIH-10894459 on ClinicalTrials.gov

What this research studies

This research focuses on understanding the role of hyaluronic acid and its receptors in the development of endometriosis, a condition affecting many women. The study aims to explore how endometrial cells attach to other cells in the body, leading to the formation of endometriotic lesions. By examining the mechanisms involved, including the impact of a drug called Hymecromone that inhibits hyaluronic acid production, the research seeks to uncover potential therapeutic targets for treating endometriosis.

Who could benefit from this research

Good fit: Ideal candidates for this research are women of reproductive age who have been diagnosed with endometriosis.

Not a fit: Patients who do not have endometriosis or are not of reproductive age may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments for endometriosis, improving the quality of life for affected patients.

How similar studies have performed: Previous research has shown promising results in understanding the role of hyaluronic acid in other conditions, suggesting potential for success in this area as well.

Where this research is happening

SAN ANTONIO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.