Investigating how HIV and cigarette smoke contribute to lung disease
The Role of HuR in HIV related COPD
This study is looking at how HIV and cigarette smoke can make lung problems worse for people living with HIV, and it hopes to find new ways to help improve lung health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Suny Downstate Medical Center NIH-funded |
| Lab location | 1 site (Brooklyn, United States) |
| Project ID | NIH-10867333 on NIH RePORTER |
What this research studies
This research focuses on understanding the relationship between HIV infection and the development of chronic obstructive pulmonary disease (COPD), particularly how cigarette smoke exacerbates this condition in people living with HIV. The study will analyze the effects of cigarette smoke on lung cells and the role of a specific protein, HuR, which is crucial for regulating cell responses. By examining both laboratory models and human samples, the research aims to uncover mechanisms that lead to worsened lung health in this population, potentially leading to new treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who also have a history of cigarette smoking or are at risk for developing COPD.
Not a fit: Patients who do not have HIV or who have never smoked may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and better lung health for individuals living with HIV who are at risk for COPD.
How similar studies have performed: Previous studies have shown a strong link between HIV and COPD, indicating that this research builds on established findings rather than exploring an entirely novel area.
Where this research is happening
Brooklyn, United States
- Suny Downstate Medical Center — Brooklyn, United States (Active)
Researchers
- Principal investigator: Foronjy, Robert F — Suny Downstate Medical Center
- Study coordinator: Foronjy, Robert F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.