Investigating how HIV affects heart and lung health
Exploratory Research on HIV Contribution to Heart and Lung Comorbidities
This study is looking at how HIV affects heart and lung health, especially by checking how tiny particles released by cells might make these problems worse, even for people who are getting good treatment for HIV.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project ID | NIH-10569641 on NIH RePORTER |
What this research studies
This research explores the impact of HIV infection on cardiovascular and pulmonary health, particularly focusing on how endothelial cell dysfunction contributes to these complications. The study examines the role of extracellular vesicles, which are tiny particles released by cells, in influencing inflammation and disease progression in patients with chronic HIV. By analyzing these vesicles, researchers aim to understand how they may carry viral proteins and other factors that exacerbate heart and lung issues, even in patients receiving effective antiretroviral therapy.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with chronic HIV who are experiencing cardiovascular or pulmonary issues.
Not a fit: Patients without HIV or those who do not have any cardiovascular or pulmonary complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing heart and lung complications in HIV patients.
How similar studies have performed: Previous research has shown promising results in understanding the role of extracellular vesicles in HIV-related complications, indicating that this approach has potential for success.
Where this research is happening
New Orleans, United States
- Tulane University of Louisiana — New Orleans, United States (Active)
Researchers
- Principal investigator: Maclean, Andrew G — Tulane University of Louisiana
- Study coordinator: Maclean, Andrew G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.