Investigating how HIV affects cancer outcomes and aging in patients
HIV Genomic Aging Project in Oncology (HIV-GAP)
This study is looking at how HIV affects cancer outcomes in older patients by finding signs of aging in those with HIV and cancer, so we can better understand why they might have worse results and improve their treatment options.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-10900674 on NIH RePORTER |
What this research studies
This research focuses on understanding the relationship between HIV and cancer outcomes, particularly in older patients. It aims to identify biological markers that indicate accelerated aging in individuals with HIV who have cancer. By comparing the biological age of cancer patients with and without HIV, the study seeks to uncover factors that contribute to poorer cancer prognosis in those with HIV. The methodology includes analyzing genomic biomarkers and their association with clinical outcomes to provide insights into improving treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who are living with HIV and have been diagnosed with cancer.
Not a fit: Patients who are younger than 65 or do not have HIV-related cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved cancer treatment and outcomes for patients living with HIV.
How similar studies have performed: Previous studies have indicated that HIV-infected individuals experience accelerated biological aging, suggesting that this research builds on established findings in the field.
Where this research is happening
Tampa, United States
- H. Lee Moffitt Cancer Ctr & Res Inst — Tampa, United States (Active)
Researchers
- Principal investigator: Coghill, Anna — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Coghill, Anna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.