NIH-funded research NIH-funded research

Investigating how heart medications may affect cognitive decline in older adults

Official title: Estimating the treatment effect of cardiovascular medications to modify the risk for future cognitive decline in older adults

Funded at Yale University · NIH-11192868 · Data updated 2026-11-12

This study is looking at how heart medications might affect thinking and memory in older adults, with the goal of helping them live better lives as they age.

More Cognitive Decline research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startSeptember 15, 2024
Project endMay 31, 2029
Funding year2025
Award (this year)$243,000
NIH project number5K76AG088428-02
Project IDNIH-11192868 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults who are currently prescribed cardiovascular medications and are at risk for cognitive decline.

Less likely to help

Patients who are younger than 21 or those not taking cardiovascular medications may not benefit from this research.

What this research studies

This research focuses on understanding the effects of cardiovascular medications on cognitive health in older adults. By examining how these treatments may influence the risk of cognitive decline, the study aims to provide insights into improving the quality of life for aging individuals. The research will involve a detailed analysis of patient data and outcomes, utilizing a team of experts in geriatrics and cardiology to ensure robust findings. Patients may be monitored over time to assess changes in cognitive function related to their cardiovascular treatment.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies that help preserve cognitive function in older adults taking heart medications.

How similar studies have gone: Previous research has shown promising results in understanding the relationship between cardiovascular health and cognitive function, suggesting that this approach may yield valuable insights.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Nanna, Michael — Yale University
  • Study coordinator: Nanna, Michael

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.