Investigating how gut microbes affect allergic asthma in children
Microbiome Studies
This study is looking at how tiny germs in our gut and environment might affect the chances of kids developing allergic asthma, especially by comparing children from Tucson, Arizona, and Nogales, Mexico, to find ways to help prevent and treat this condition.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-10932531 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of gut and environmental microbes in the development of allergic asthma in children, particularly comparing genetically similar children in Mexico and the U.S. The study examines how microbial exposures during pregnancy and early life may contribute to differences in asthma rates between Mexican-American children in Tucson, Arizona, and their counterparts in Nogales, Mexico. By analyzing a large number of samples, the research aims to identify specific microbial patterns that could be linked to asthma development. The findings could lead to better prevention strategies and treatments for allergic asthma in children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years, particularly those with a family history of allergic asthma or who live in areas with high asthma prevalence.
Not a fit: Patients who are older than 11 years or do not have a history of allergic asthma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for allergic asthma in children.
How similar studies have performed: Previous research has shown promising results in understanding the link between gut microbiota and asthma, suggesting that this approach could yield valuable insights.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Mccauley, Kathryn — University of Arizona
- Study coordinator: Mccauley, Kathryn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.