Investigating how gut health and vitamin D levels affect cognitive development in children with HIV.
Gut permeability and variations in bio-available vitamin D as mechanisms of adverse cognitive development in HIV-affected & control children - Anested Pilot Study
This study is looking at how vitamin D levels and gut health might affect brain development in children with HIV, and it aims to help understand the risks for learning and thinking problems in these kids.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan State University NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project ID | NIH-10742582 on NIH RePORTER |
What this research studies
This research explores the relationship between gut permeability, vitamin D deficiency, and cognitive development in children affected by HIV. It aims to understand how variations in vitamin D levels can influence gut health and, in turn, impact brain function and development. The study will collect data on nutrition, immune responses, and HIV status to create a Cognitive Risk Index that may help predict neurocognitive disorders in children. By examining these factors, the research seeks to fill knowledge gaps regarding the effects of HIV and early treatment on child development.
Who could benefit from this research
Good fit: Ideal candidates for this research include children aged 0-11 years who are living with HIV or have been exposed to HIV.
Not a fit: Children who are not affected by HIV or who do not have any developmental concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing cognitive disorders in children affected by HIV.
How similar studies have performed: Previous research has indicated that vitamin D deficiency can impact cognitive development, suggesting that this study's approach may yield valuable insights.
Where this research is happening
East Lansing, United States
- Michigan State University — East Lansing, United States (Active)
Researchers
- Principal investigator: Ezeamama, Amara E — Michigan State University
- Study coordinator: Ezeamama, Amara E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.