Investigating how gut bacteria affect health after metabolic surgery
The Gut Microbiota in Metabolic Surgery: A Multi-Ethnic, Multi-Omic, Longitudinal Study
This study is looking at how the bacteria in your gut can affect your health after weight loss surgery, especially for people with type 2 diabetes and heart issues, and it includes a diverse group of patients, including many African Americans, to make sure everyone’s experiences are understood.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11014423 on NIH RePORTER |
What this research studies
This research focuses on understanding the relationship between gut microbiota and health outcomes in patients undergoing metabolic and bariatric surgery. By studying a diverse group of patients over time, the research aims to uncover how changes in gut bacteria and their metabolites influence conditions like type 2 diabetes and cardiovascular disease. The approach includes advanced techniques to analyze the microbiota and their functions, considering factors such as diet and medication use. This study is particularly important as it includes African American patients, who are often underrepresented in similar research.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals planning to undergo metabolic or bariatric surgery, particularly those from diverse ethnic backgrounds, including African Americans.
Not a fit: Patients who are not candidates for metabolic surgery or those with unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new microbiota-based therapies that improve health outcomes for patients undergoing metabolic surgery.
How similar studies have performed: While there is limited research on gut microbiota in relation to metabolic surgery, similar studies in other areas have shown promising results, indicating potential for success in this novel approach.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Yu, Danxia — Vanderbilt University Medical Center
- Study coordinator: Yu, Danxia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.