Investigating how gut bacteria affect endometriosis
Official title: Role of the gut microbiota in endometriosis
Funded at Baylor College of Medicine · NIH-11078726 · Data updated 2026-11-12
This study is looking at how the bacteria in our gut might affect endometriosis, a condition that causes pelvic pain in women, to find out if certain bacteria can help prevent or worsen the disease, with hopes of discovering new ways to diagnose and treat it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | April 1, 2021 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $375,960 |
| NIH project number | 5R01HD102680-05 |
| Project ID | NIH-11078726 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women aged 15 to 49 who are experiencing symptoms of endometriosis, particularly chronic pelvic pain.
✕Less likely to help
Patients who do not have endometriosis or are outside the childbearing age range may not benefit from this research.
What this research studies
This research explores the relationship between gut microbiota and endometriosis, a condition that causes significant pelvic pain in women. The study aims to identify specific gut bacteria that may either promote or protect against the development of endometriosis by influencing inflammation in the body. By using animal models, the researchers will examine how these bacteria interact with the immune system and contribute to the disease process. The ultimate goal is to uncover new diagnostic and therapeutic strategies for managing endometriosis.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for endometriosis that are more effective and have fewer side effects than current options.
How similar studies have gone: Previous research has shown promising results in understanding the role of gut microbiota in various diseases, suggesting that this approach may yield valuable insights for endometriosis as well.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Kommagani, Ramakrishna — Baylor College of Medicine
- Study coordinator: Kommagani, Ramakrishna
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.