Investigating how gut bacteria affect breast health and cancer
Roles of gut-breast axis in breast pathophysiology
This study is looking at how the bacteria in our gut might affect breast health and cancer, hoping to find out if these tiny microbes can help us understand and improve treatment for breast cancer in both healthy people and those diagnosed with the disease.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11067771 on NIH RePORTER |
What this research studies
This research explores the connection between gut bacteria and breast health, particularly how these microbes may influence cancer development and treatment outcomes. It aims to determine if a 'gut-breast axis' exists outside of pregnancy and how different bacteria may affect healthy individuals compared to those with breast cancer. By analyzing specific gut microbiotas from animal models, the study seeks to uncover the roles these bacteria play in either promoting or preventing tumor growth. The findings could provide insights into new therapeutic strategies for breast cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with breast cancer as well as healthy individuals interested in breast health.
Not a fit: Patients who do not have breast health concerns or those who are not interested in the role of gut microbiota in health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that harness the power of gut bacteria to improve breast cancer outcomes.
How similar studies have performed: While the concept of the gut-breast axis is relatively novel, preliminary studies have shown promising results in understanding the role of microbiota in cancer development.
Where this research is happening
Cleveland, United States
- Case Western Reserve University — Cleveland, United States (Active)
Researchers
- Principal investigator: Furuta, Saori — Case Western Reserve University
- Study coordinator: Furuta, Saori
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.