Investigating how gut bacteria affect Alzheimer's disease
Project 3 - Mechanistic studies on role of gut microbiome in models for Alzheimer's disease
This study is looking at how the health of your gut might affect your brain, especially for people with Alzheimer's, by exploring how gut bacteria can influence thinking and memory.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10693932 on NIH RePORTER |
What this research studies
This research explores the connection between the gut microbiome and brain health, particularly in relation to Alzheimer's disease. It examines how signals from the gastrointestinal tract influence brain activity and psychological responses. By studying the metabolites produced by gut bacteria, the research aims to uncover the mechanisms through which gut health may impact cognitive function and the progression of Alzheimer's. Patients may be involved in understanding how their gut health correlates with their cognitive status.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or those at risk of developing it.
Not a fit: Patients with non-neurological conditions or those without any cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating Alzheimer's disease by targeting gut health.
How similar studies have performed: Other research has shown promising results in understanding the gut-brain connection, suggesting that this approach could yield significant insights.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Kaddurah-Daouk, Rima F — Duke University
- Study coordinator: Kaddurah-Daouk, Rima F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.