Investigating how Group B Streptococcus affects diabetic wound infections
Host-pathogen interactions during GBS diabetic wound infections
This study is looking at how a common germ called Group B Streptococcus affects wounds in people with diabetes, hoping to find ways to help these wounds heal better.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11094680 on NIH RePORTER |
What this research studies
This research focuses on understanding the interactions between Group B Streptococcus (GBS) and diabetic wounds. It aims to explore how GBS, a common bacterium, contributes to infections in individuals with diabetes, particularly those with chronic wounds. The study utilizes advanced techniques like dual RNA-sequencing to analyze infected tissues and identify key metal transport systems that may influence the infection process. By examining these interactions, the research seeks to uncover potential targets for improving wound healing in diabetic patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have diabetes and are experiencing chronic wounds.
Not a fit: Patients without diabetes or those who do not have chronic wounds may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating infections in diabetic patients with chronic wounds.
How similar studies have performed: Previous research has shown success in understanding bacterial infections in diabetic wounds, indicating that this approach has potential for meaningful insights.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Akbari, Madeline Sohayla — University of Colorado Denver
- Study coordinator: Akbari, Madeline Sohayla
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.