Investigating how genital bacteria influence HIV risk

How sex, host microenvironment, and immune responses shape acquisition of genital bacteria that increase HIV risk

NIH-funded research George Washington University · NIH-10993139

This study is looking at how certain bacteria in the genital area might influence the risk of getting HIV, with the hope of finding new ways to help prevent the virus, so people can better understand how their own bacteria might affect their HIV risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorge Washington University NIH-funded
Lab location1 site (Washington, United States)
Project IDNIH-10993139 on NIH RePORTER

What this research studies

This research explores the relationship between certain genital bacteria and the risk of acquiring HIV, particularly focusing on how these bacteria can affect immune responses. By studying the factors that contribute to the presence and persistence of these bacteria in the genital microbiome, the research aims to uncover new insights into HIV transmission dynamics. The project will involve analyzing both biological and environmental factors that influence the genital microbiome, with the goal of developing innovative prevention strategies against HIV. Patients may benefit from a better understanding of how their microbiome affects their HIV risk.

Who could benefit from this research

Good fit: Ideal candidates for this research include sexually active individuals, particularly men, who may be at risk for HIV due to the presence of certain genital bacteria.

Not a fit: Patients who are not sexually active or those who do not have any risk factors for HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing HIV transmission by targeting specific genital bacteria.

How similar studies have performed: Other research has indicated that understanding the microbiome can influence HIV transmission, suggesting that this approach has potential for success.

Where this research is happening

Washington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.