Investigating how genetics influence resistance to parasites in different environments
A general test of the genetic basis of parasite resistance across genetic and environmental contexts
This study is looking at how our genes help us fight off parasites, and it’s for anyone curious about why some people are better at resisting infections than others, depending on where they live.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-10861843 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic factors that determine how well individuals can resist parasites, which can vary based on their environment. By studying a variety of organisms, including humans, the researchers aim to identify specific genetic variations that contribute to parasite resistance. They will analyze genetic diversity and environmental influences to uncover why certain genetic traits may work in some contexts but not in others. This comprehensive approach will help to better understand the complexities of disease susceptibility and resistance.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a history of parasitic infections or those interested in genetic factors affecting disease susceptibility.
Not a fit: Patients who do not have any history of parasitic infections or genetic predispositions related to parasite resistance may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating parasitic infections in patients.
How similar studies have performed: Previous research has shown promise in identifying genetic factors related to disease resistance, but this study aims to explore these factors in a more diverse and natural context, making it a novel approach.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Gibson, Amanda K — University of Virginia
- Study coordinator: Gibson, Amanda K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.