Investigating how genetics and race affect bone health in children with kidney disease
Vitamin D Genetics and Racial Differences in Pediatric Chronic KidneyDisease-Mineral and Bone Disorder
This study is looking at how genes affect bone health in kids with chronic kidney disease, so we can better understand how they might respond to treatments with Vitamin D and parathyroid hormone, ultimately helping to improve their overall health and quality of life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-11044367 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic factors that influence bone health and mineral metabolism in children with chronic kidney disease (CKD). The study aims to identify genetic variants that may predict how these patients respond to treatments involving Vitamin D and parathyroid hormone (PTH). By analyzing epidemiological data and employing advanced statistical methods, the research seeks to tailor treatments to improve health outcomes for pediatric CKD patients. The ultimate goal is to enhance the quality of life for these children by addressing the high rates of skeletal and cardiovascular issues associated with CKD.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and adolescents under 21 years old who have been diagnosed with chronic kidney disease.
Not a fit: Patients who do not have chronic kidney disease or those over the age of 21 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for children suffering from chronic kidney disease-related bone disorders.
How similar studies have performed: Previous research has shown promising results in understanding genetic influences on bone health, suggesting that this approach could yield valuable insights.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Laster, Marciana Lee — Indiana University Indianapolis
- Study coordinator: Laster, Marciana Lee
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.