Investigating how genetic changes at birth relate to asthma in children
Clusters of Epigenetic Networks at Birth and Asthma Incidence in Children
This study is looking at how certain genes work together to help us understand why some kids and young adults develop asthma, so we can learn more about the risk factors involved.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Memphis NIH-funded |
| Lab location | 1 site (Memphis, United States) |
| Project ID | NIH-10933410 on NIH RePORTER |
What this research studies
This research explores the epigenetic factors that may contribute to the development of asthma in children and young adults. By examining how genes work together rather than in isolation, the study aims to identify specific genetic networks that influence asthma risk. The methodology involves analyzing DNA methylation patterns and constructing networks of gene interactions to better understand their collective impact on asthma incidence. This approach seeks to address the limitations of previous studies that focused on individual genetic contributions.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and young adults, particularly those with a family history of asthma or other respiratory conditions.
Not a fit: Patients who are older than 20 years or do not have a history of asthma or related respiratory issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for asthma in children.
How similar studies have performed: While the approach of examining epigenetic networks is gaining traction, this specific methodology addressing heterogeneity in asthma risk is relatively novel and has not been extensively tested.
Where this research is happening
Memphis, United States
- University of Memphis — Memphis, United States (Active)
Researchers
- Principal investigator: Zhang, Hongmei — University of Memphis
- Study coordinator: Zhang, Hongmei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.