Investigating how genetic changes affect endometriosis and potential new treatments
Epigenetic regulatory mechanisms and therapeutic opportunities in endometriosis
This study is looking at how endometriosis works at a molecular level to help find new, non-hormonal treatments, and women with the condition may have a chance to get involved and contribute to the research.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan State University NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project ID | NIH-10886711 on NIH RePORTER |
What this research studies
This research focuses on understanding the molecular mechanisms behind endometriosis, a condition affecting many women and causing pain and infertility. By studying the genetic and epigenetic changes in endometrial cells, the research aims to identify how these cells invade and survive outside the uterus. The project will use advanced technologies to analyze the genome and epigenome, which could lead to the development of non-hormonal treatment options specifically targeting the disease. Patients may have the opportunity to contribute to this research through participation in innovative model systems.
Who could benefit from this research
Good fit: Ideal candidates for this research are women of reproductive age who are experiencing symptoms of endometriosis, such as chronic pelvic pain or infertility.
Not a fit: Patients who do not have endometriosis or are not experiencing related symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, targeted treatments for endometriosis that do not rely on hormones.
How similar studies have performed: Previous research has shown promise in understanding the genetic factors of endometriosis, but this approach focusing on epigenetic mechanisms is relatively novel.
Where this research is happening
East Lansing, United States
- Michigan State University — East Lansing, United States (Active)
Researchers
- Principal investigator: Chandler, Ronald L — Michigan State University
- Study coordinator: Chandler, Ronald L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.