Investigating how genetic and epigenetic factors affect health outcomes after viral infections.
Host Genetic and Epigenetic Factors of the Progression, Comorbidities and Outcomes of Viral Infection
This study is looking at how our genes and other factors affect how viral infections like HIV and COVID-19 progress and impact health, especially for veterans, to help find ways to predict and improve health outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Decatur, UNITED STATES) |
| Project ID | NIH-10950351 on NIH RePORTER |
What this research studies
This research focuses on understanding how genetic and epigenetic factors influence the progression and outcomes of viral infections such as HIV and SARS-CoV-2. By analyzing host responses and health outcomes, the study aims to uncover the links between viral infections and chronic diseases, particularly in veterans. The methodology includes genome-wide association studies and epigenome-wide association studies to identify markers that could predict health complications and aging processes related to these infections.
Who could benefit from this research
Good fit: Ideal candidates for this research include veterans who have been infected with HIV, HCV, or SARS-CoV-2.
Not a fit: Patients who have not been infected with the aforementioned viruses may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of health outcomes for patients with viral infections.
How similar studies have performed: Previous studies have shown success in identifying genetic and epigenetic markers related to chronic diseases, suggesting a promising avenue for this research.
Where this research is happening
Decatur, UNITED STATES
- Veterans Health Administration — Decatur, United States (Active)
Researchers
- Principal investigator: Marconi, Vincent Charles — Veterans Health Administration
- Study coordinator: Marconi, Vincent Charles
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.