Investigating how genetic ancestry affects the risk of Acute Lymphoblastic Leukemia in Latino children
Exploring the Impact of Genetic Ancestry on Acute Lymphoblastic Leukemia Risk in Latino Populations
This study is looking at how genes might affect the risk of Acute Lymphoblastic Leukemia (ALL) in Latino children, so we can better understand why this group is more affected and improve prevention and treatment options just for them.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10983728 on NIH RePORTER |
What this research studies
This research aims to understand the genetic factors that contribute to the risk of Acute Lymphoblastic Leukemia (ALL) specifically in Latino populations. By employing advanced gene discovery techniques, the study will analyze genetic data from a large group of Latino children diagnosed with ALL compared to healthy controls. The goal is to identify how different ancestral backgrounds influence the likelihood of developing this type of leukemia, which has been shown to have higher incidence and poorer outcomes in Latino children. This research will also enhance methods for studying genetic risks in diverse populations, potentially leading to more tailored prevention and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are Latino children diagnosed with Acute Lymphoblastic Leukemia, as well as healthy Latino children for comparison.
Not a fit: Patients who do not identify as Latino or who are over the age of 20 may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of Acute Lymphoblastic Leukemia in Latino children, potentially resulting in better outcomes and targeted therapies.
How similar studies have performed: Previous research has shown that genetic ancestry can influence cancer risk, but this specific focus on Latino populations and ALL is relatively novel.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Langie, Jalen — University of Southern California
- Study coordinator: Langie, Jalen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.