Investigating how genes and environmental factors interact to influence disease risk
Genome-wide screen for dynamic gene-environment interactions
This study is looking at how your genes and the environment around you can work together to influence your risk of getting certain diseases, and it aims to create better tools to help understand these connections so that you can learn more about your own genetic risks.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10703433 on NIH RePORTER |
What this research studies
This research focuses on understanding how genetic factors and environmental exposures work together to affect the risk of developing complex diseases. By incorporating gene-environment interactions into genome-wide association studies (GWAS), the researchers aim to enhance the detection of genetic variants that contribute to disease susceptibility. The study will develop new methods and software tools to analyze these interactions, allowing for more accurate identification of genetic associations. Patients may benefit from improved understanding of their genetic risks in relation to environmental factors.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a family history of complex diseases or those exposed to specific environmental risk factors.
Not a fit: Patients with purely genetic diseases that do not involve environmental interactions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better identification of genetic risks for diseases, allowing for more personalized prevention and treatment strategies.
How similar studies have performed: Previous research has shown that incorporating gene-environment interactions can significantly enhance the understanding of disease susceptibility, indicating a promising approach.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Xing, Chao — Ut Southwestern Medical Center
- Study coordinator: Xing, Chao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.