Investigating how genes and environmental factors interact in autism
Gene-Environment interactions in Autism
['FUNDING_R01'] · EMORY UNIVERSITY · NIH-10992111
This study is looking at how genes and environmental factors, like certain chemicals, might affect children with autism, and it involves collecting samples from kids to help us learn more about how these things can influence their development and behavior.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EMORY UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-10992111 on ClinicalTrials.gov |
What this research studies
This research explores the relationship between genetic variations and environmental influences in children with autism spectrum disorder (ASD). By examining induced pluripotent stem cells (iPSCs) from both typical and ASD-affected individuals, the study aims to understand how exposure to environmental chemicals, like bisphenol A (BPA), may affect gene regulation and contribute to ASD symptoms. The approach includes advanced sequencing techniques to identify how these interactions may lead to changes in brain development and behavior. Patients may be involved in providing biological samples to help uncover these critical interactions.
Who could benefit from this research
Good fit: Ideal candidates for participation are children aged 0-11 years who have been diagnosed with autism spectrum disorder.
Not a fit: Patients who do not have autism spectrum disorder or are older than 11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potentially new interventions for autism spectrum disorder.
How similar studies have performed: Previous research has shown promising results in understanding gene-environment interactions in other neurodevelopmental disorders, suggesting potential for success in this area as well.
Where this research is happening
ATLANTA, UNITED STATES
- EMORY UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CORCES, VICTOR G. — EMORY UNIVERSITY
- Study coordinator: CORCES, VICTOR G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.