Investigating how GAS6 helps heal and regenerate jawbone after tooth loss
GAS6-mediated alveolar bone regeneration
This study is looking at how a protein called GAS6 helps heal the bone and tissues in your mouth after a tooth is pulled, with the goal of finding better ways to help people who have lost teeth due to injury or illness.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10908587 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of a protein called GAS6 in the healing process of alveolar bone and oral tissues after tooth extraction. By studying mice and patient-derived cells, the researchers aim to uncover how GAS6 influences the behavior of stem cells and immune responses during tissue regeneration. The project seeks to improve the predictability of bone regeneration techniques, which can significantly impact patients who have lost teeth due to trauma or disease. Through this work, the researchers hope to develop more effective treatments for restoring oral function and aesthetics.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced tooth loss due to trauma or disease and are seeking options for bone regeneration.
Not a fit: Patients who do not have any history of tooth loss or those with conditions that prevent healing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for regenerating jawbone and oral tissues, enhancing recovery after tooth loss.
How similar studies have performed: Previous research has shown promising results in understanding the role of growth factors in tissue regeneration, suggesting that this approach may yield valuable insights.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Decker, Ann Marie — University of Michigan at Ann Arbor
- Study coordinator: Decker, Ann Marie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.