Investigating how G-proteins and cell adhesion proteins control cell growth and movement
Structure and Mechanism of G-proteins and cell adhesion proteins in regulation of cell growth and motility
This study is looking at how certain proteins help control how cells grow and move, which could be important for understanding diseases, and it's for anyone interested in how our cells work.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11011692 on NIH RePORTER |
What this research studies
This research explores the mechanisms by which G-proteins and cell adhesion proteins influence cell growth and motility. It focuses on understanding how G-proteins are activated and how they signal within cells, challenging traditional views on their regulation. The study employs a variety of methods, including computational modeling and biochemical assays, to uncover new insights into these processes. Additionally, it examines the roles of specific proteins in maintaining cell structure and function, which could have implications for various diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to abnormal cell growth or motility, including certain cancers and cardiovascular diseases.
Not a fit: Patients with stable, non-progressive conditions unrelated to cell growth or motility may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for diseases related to cell growth and movement, such as cancer and cardiovascular disorders.
How similar studies have performed: Previous research has shown promising results in understanding G-protein signaling and its implications for disease, suggesting that this approach could yield valuable insights.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Campbell, Sharon L — Univ of North Carolina Chapel Hill
- Study coordinator: Campbell, Sharon L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.