Investigating how Foxp2 affects the auditory pathway development
Official title: The Foxp2 Influence on the Developing Auditory Pathway
Funded at Ut Southwestern Medical Center · NIH-11116838 · Data updated 2026-11-12
This study is looking at how a gene called Foxp2 affects hearing and sound processing in people with autism, to better understand why some may be more sensitive to sounds.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | June 1, 2024 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $40,691 |
| NIH project number | 5F30DC022213-02 |
| Project ID | NIH-11116838 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals under 21 years old diagnosed with autism spectrum disorder who experience sensory hyper- or hyposensitivity.
✕Less likely to help
Patients without autism spectrum disorder or those over 21 years old may not benefit from this research.
What this research studies
This research explores the role of the Foxp2 gene in the development of the auditory pathway, particularly in individuals with autism spectrum disorder (ASD). By examining brain regions involved in auditory processing, the study aims to understand how mutations in Foxp2 may contribute to sensory sensitivities commonly seen in neurodevelopmental disorders. The research employs advanced techniques like single nuclei RNA sequencing and chromatin accessibility analysis to identify changes at the cellular level. This approach will help clarify the mechanisms by which Foxp2 influences auditory processing and sensory behaviors.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential interventions for sensory processing issues in patients with autism.
How similar studies have gone: Previous research has shown promising results in understanding the role of genetic factors like Foxp2 in neurodevelopmental disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Jankovic, Miranda — Ut Southwestern Medical Center
- Study coordinator: Jankovic, Miranda
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.