Investigating how FGF21 affects metabolic syndrome after undernutrition refeeding

Who could benefit from this research

What this research studies

This research explores the impact of undernutrition during childhood on the development of metabolic syndrome (MetS) later in life, particularly after refeeding. It aims to understand how the loss of a protein called FGF21 may contribute to obesity, insulin resistance, and other metabolic issues. By using mouse models, the study will compare the effects of refeeding on normal mice and those lacking FGF21, focusing on behaviors like food preference and overeating. The findings could provide insights into the biological mechanisms behind MetS and potential interventions.

Why it matters

Where this research is happening

• University of Texas Med Br Galveston
  Galveston, United States Active

Researchers

• Principal investigator: Osorio, Elvia Janeth — University of Texas Med Br Galveston
• Study coordinator: Osorio, Elvia Janeth

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.