Investigating how fat metabolism affects colorectal cancer spread
Targeting Lipid Metabolism in Colorectal Cancer
This study is looking at how fat processing in the body affects the spread of colorectal cancer, focusing on a special enzyme that might help us find new ways to treat and slow down cancer growth for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-11061254 on NIH RePORTER |
What this research studies
This research focuses on understanding how changes in fat metabolism contribute to the spread of colorectal cancer (CRC). The team aims to explore the role of a key enzyme, fatty acid synthase (FASN), which is linked to poor outcomes in CRC patients. By studying how FASN influences the production of specific lipids that may promote cancer metastasis, the researchers hope to identify new therapeutic targets. Patients may benefit from potential new treatments that could prevent or reduce the spread of their cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with colorectal cancer, particularly those with advanced stages or metastatic disease.
Not a fit: Patients with early-stage colorectal cancer or those whose cancer is not related to lipid metabolism may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments that specifically target the spread of colorectal cancer.
How similar studies have performed: Previous research has shown promising results in targeting lipid metabolism in cancer, suggesting that this approach may lead to significant advancements in treatment.
Where this research is happening
Lexington, United States
- University of Kentucky — Lexington, United States (Active)
Researchers
- Principal investigator: Zaytseva, Yekaterina — University of Kentucky
- Study coordinator: Zaytseva, Yekaterina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.