Investigating how Fasciola hepatica spreads among humans and animals to improve control strategies.
One-Health Approach to Study Human Fasciola hepatica Transmission and Inform Strategic Control
This study is looking at how the Fasciola hepatica parasite spreads, especially among school-age kids in rural areas of Peru, to find out what puts them at risk and how well the current treatment works, so we can come up with better ways to prevent and control this infection.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Med Br Galveston NIH-funded |
| Lab location | 1 site (Galveston, United States) |
| Project ID | NIH-11054671 on NIH RePORTER |
What this research studies
This research focuses on understanding the transmission of the Fasciola hepatica parasite, which causes fascioliasis, particularly in school-age children in rural communities. By employing a One Health approach, the study will analyze the interactions between humans, animals, and the environment in the Peruvian highlands. The research aims to identify risk factors for human infection and evaluate the effectiveness of current treatment methods, particularly the drug triclabendazole. Through this comprehensive analysis, the study seeks to develop better strategies for controlling and preventing fascioliasis.
Who could benefit from this research
Good fit: Ideal candidates for this research include school-age children living in rural areas of Peru who are at risk of fascioliasis.
Not a fit: Patients who do not reside in endemic areas or who are not school-age children may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for fascioliasis, ultimately reducing the disease burden in affected communities.
How similar studies have performed: Previous research has shown success in using a One Health approach to address zoonotic diseases, indicating potential for this study's methodology.
Where this research is happening
Galveston, United States
- University of Texas Med Br Galveston — Galveston, United States (Active)
Researchers
- Principal investigator: Cabada, Miguel Mauricio — University of Texas Med Br Galveston
- Study coordinator: Cabada, Miguel Mauricio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.