Investigating how exposure to WTC dust affects prostate cancer recurrence
Official title: Assessing the impact of WTC dust exposure on prostate cancer recurrence
Funded at Icahn School of Medicine at Mount Sinai · NIH-10905975 · Data updated 2026-11-12
This study is looking at whether breathing in dust from the World Trade Center during the 9/11 attacks might be linked to prostate cancer coming back, and it's for people who were exposed to that dust and want to understand how it could affect their health over time.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $499,998 |
| NIH project number | 5U01OH012628-02 |
| Project ID | NIH-10905975 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who were exposed to WTC dust during the 9/11 attacks and have a history of prostate cancer.
✕Less likely to help
Patients who have not been exposed to WTC dust or do not have a history of prostate cancer may not benefit from this research.
What this research studies
This research examines the potential link between exposure to dust from the World Trade Center (WTC) during the 9/11 attacks and the recurrence of prostate cancer. It focuses on understanding how carcinogens and inflammation from the dust may influence cancer progression. The study will analyze data from individuals exposed to WTC dust and assess their cancer outcomes over time, utilizing advanced methodologies including RNA expression and DNA methylation analyses. By collaborating with the WTC Health Program, the research aims to provide insights into the long-term health effects of this exposure.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment strategies for prostate cancer in individuals exposed to WTC dust.
How similar studies have gone: Previous studies have indicated increased cancer rates among WTC dust-exposed populations, suggesting that this research builds on established findings rather than being entirely novel.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Aaronson, Stuart a — Icahn School of Medicine at Mount Sinai
- Study coordinator: Aaronson, Stuart a
Related research
Other NIH-funded projects on the same topics.
-
Understanding why some WTC-related prostate cancers come back
A study uses advanced tissue mapping to find why prostate cancer recurs in World Trade Center responders.
-
Understanding WTC Dust Exposure and Prostate Cancer
This project looks at how exposure to World Trade Center dust might affect prostate cancer in people who were there during 9/11.
-
Keloid recurrence study using multi-omics in diverse patients
A research effort will look at why keloids come back after surgery, especially in African American patients, using comprehensive molecular data from patient samples.
-
Cardiovascular risk planning and reduction for men with prostate cancer
A program to better predict and reduce heart disease risk in men treated for prostate cancer, especially older patients.
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Effects of ADT on motivation and emotion in prostate cancer patients
This project looks at how androgen deprivation therapy may affect motivation and mood over time in men with prostate cancer.
-
Causal Protein Markers to Understand and Predict Prostate Cancer Risk in Africans and Europeans
A cancer research project looking at proteins linked to prostate cancer to better understand why it happens and how risk differs between African and European populations.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.