Investigating how exposure to residential bioaerosols affects lung health in sarcoidosis patients
The Role of Residential Bioaerosol Exposure in Pulmonary Sarcoidosis
This study is looking at how tiny particles in the air at home might affect people with pulmonary sarcoidosis, helping us understand if these particles could make their lung condition worse.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project ID | NIH-11160190 on NIH RePORTER |
What this research studies
This research explores the connection between exposure to bioaerosols in residential environments and the severity of pulmonary sarcoidosis, a rare inflammatory disease that primarily affects the lungs. The study will involve collecting samples of bioaerosols from the homes of patients and analyzing their composition to identify potential environmental triggers. Researchers will also assess the immune response in patients with varying degrees of lung disease severity, comparing their immune profiles and symptoms to those of healthy controls. The goal is to better understand how these exposures may lead to worsening lung conditions in sarcoidosis patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pulmonary sarcoidosis, particularly those experiencing severe symptoms or lung impairment.
Not a fit: Patients with sarcoidosis who have mild symptoms or are not experiencing significant lung issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of pulmonary sarcoidosis, potentially reducing morbidity and mortality associated with the disease.
How similar studies have performed: Previous research has indicated a link between environmental exposures and sarcoidosis, but this specific investigation into residential bioaerosols is relatively novel.
Where this research is happening
Iowa City, United States
- University of Iowa — Iowa City, United States (Active)
Researchers
- Principal investigator: Gerke, Alicia — University of Iowa
- Study coordinator: Gerke, Alicia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.