NIH-funded research R01 grant

Investigating how exposure to radioactive particles affects heart health.

Official title: A nationwide population-based study investigating the cardiovascular effects of exposure to particulate matter α-, β-, and γ-activities and individual radionuclides

Funded at Harvard School of Public Health · NIH-11061360 · Data updated 2026-11-12

This study looks at how breathing in tiny bits of radioactive material might affect heart health, especially for older adults on Medicare, to help everyone understand the connection between our environment and heart disease.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard School of Public Health
NIH-funded
Lab location1 site (Boston, United States)
Project startApril 1, 2024
Project endJanuary 31, 2029
Funding year2025
Award (this year)$649,282
NIH project number5R01ES035390-02
Project IDNIH-11061360 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals with existing cardiovascular conditions or those living in areas with high levels of particulate air pollution.

Less likely to help

Patients with no exposure to particulate air pollution or those without cardiovascular risk factors may not benefit from this research.

What this research studies

This research examines the impact of exposure to radioactive particulate matter on cardiovascular health across the United States. By analyzing data from the U.S. EPA Radiation Network, the study aims to understand both short- and long-term effects of these exposures on heart disease and related health issues. The research will focus on various metrics of radioactive exposure and their correlation with cardiovascular disease admissions, particularly among Medicare enrollees. Patients may benefit from insights into how environmental factors contribute to heart health.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for cardiovascular diseases linked to air pollution.

How similar studies have gone: Previous studies have shown associations between air pollution and cardiovascular health, but this research aims to explore the specific effects of radioactive particulate matter, making it a novel approach.

Where this research is happening

  • Harvard School of Public Health
    Boston, United States
    Active

Researchers

  • Principal investigator: Zanobetti, Antonella — Harvard School of Public Health
  • Study coordinator: Zanobetti, Antonella

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.