Investigating how exposure to hexavalent chromium affects muscle growth and healing
Official title: Cr(VI) exposure and skeletal muscle differentiation and regeneration
Funded at New York University School of Medicine · NIH-11135847 · Data updated 2026-11-12
This study is looking at how exposure to a chemical called hexavalent chromium (Cr(VI)), which is often found in different industries, might hurt muscles and make it harder for the body to heal them, and it's for anyone interested in understanding the health effects of this chemical.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2024 |
| Project end | August 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $548,707 |
| NIH project number | 1R56ES036591-01 |
| Project ID | NIH-11135847 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have been exposed to hexavalent chromium in occupational settings or through environmental sources.
✕Less likely to help
Patients who have not been exposed to hexavalent chromium or do not have muscle injury concerns may not benefit from this research.
What this research studies
This research examines the effects of hexavalent chromium (Cr(VI)), a chemical commonly used in various industries, on muscle differentiation and regeneration. The study aims to understand how exposure to Cr(VI) may lead to muscle injury and hinder the body's ability to repair itself. By using both animal models and human data, the researchers will analyze changes in muscle cells and the expression of important regulatory factors involved in muscle development. The findings could provide insights into the broader health impacts of Cr(VI) exposure.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of muscle injuries related to environmental and occupational exposures.
How similar studies have gone: While there is evidence of muscle injury related to Cr(VI) exposure in preliminary studies, this specific investigation into muscle differentiation and regeneration is relatively novel.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Sun, Hong — New York University School of Medicine
- Study coordinator: Sun, Hong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.