Investigating how exposure to hexavalent chromium affects muscle growth and healing
Cr(VI) exposure and skeletal muscle differentiation and regeneration
This study is looking at how exposure to a chemical called hexavalent chromium (Cr(VI)), which is often found in different industries, might hurt muscles and make it harder for the body to heal them, and it's for anyone interested in understanding the health effects of this chemical.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11135847 on NIH RePORTER |
What this research studies
This research examines the effects of hexavalent chromium (Cr(VI)), a chemical commonly used in various industries, on muscle differentiation and regeneration. The study aims to understand how exposure to Cr(VI) may lead to muscle injury and hinder the body's ability to repair itself. By using both animal models and human data, the researchers will analyze changes in muscle cells and the expression of important regulatory factors involved in muscle development. The findings could provide insights into the broader health impacts of Cr(VI) exposure.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have been exposed to hexavalent chromium in occupational settings or through environmental sources.
Not a fit: Patients who have not been exposed to hexavalent chromium or do not have muscle injury concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of muscle injuries related to environmental and occupational exposures.
How similar studies have performed: While there is evidence of muscle injury related to Cr(VI) exposure in preliminary studies, this specific investigation into muscle differentiation and regeneration is relatively novel.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Sun, Hong — New York University School of Medicine
- Study coordinator: Sun, Hong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.