Investigating how exposure to environmental metals affects the risk of Langerhans cell histiocytosis in children
Evaluating environmental metals exposure on risk of LCH
['FUNDING_R01'] · BAYLOR COLLEGE OF MEDICINE · NIH-10830151
This study is looking at how certain metals in the environment might be linked to Langerhans cell histiocytosis in children, especially focusing on Hispanic kids who might be more exposed to these metals, to help find ways to prevent and treat this condition better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR COLLEGE OF MEDICINE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10830151 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the potential link between exposure to environmental metals, such as arsenic, cadmium, and chromium, and the risk of developing Langerhans cell histiocytosis (LCH) in children. The study aims to explore genetic mechanisms and environmental factors that may contribute to the incidence of LCH, particularly among Hispanic children who may have higher exposure to these toxicants. By analyzing data and conducting epidemiological assessments, the research seeks to identify risk factors that could lead to better prevention and treatment strategies for this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research include children aged 0-19 years, particularly those from Hispanic backgrounds or those with known exposure to environmental metals.
Not a fit: Patients who are older than 19 years or those without any known exposure to environmental metals may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for LCH, potentially reducing its incidence and severity in affected children.
How similar studies have performed: Previous studies have suggested a link between environmental exposures and various health conditions, indicating that this research could build on existing knowledge, though the specific focus on LCH and environmental metals is relatively novel.
Where this research is happening
HOUSTON, UNITED STATES
- BAYLOR COLLEGE OF MEDICINE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SCHEURER, MICHAEL E. — BAYLOR COLLEGE OF MEDICINE
- Study coordinator: SCHEURER, MICHAEL E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.