Investigating how exposure to certain chemicals during pregnancy and menopause affects bone health and body composition.
Relating phthalate and metals exposure during pregnancy and perimenopause to bone health and body composition in midlife
This study is looking at how everyday chemicals like phthalates and heavy metals might affect bone health and body changes in women who are pregnant or going through menopause, and it’s for women who want to learn more about the potential risks of these substances during important times in their lives.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10899764 on NIH RePORTER |
What this research studies
This research examines the impact of phthalates and heavy metals on bone health and body composition in women during pregnancy and perimenopause. It aims to understand how these chemicals, commonly found in everyday products, may disrupt hormonal balance and bone metabolism. By analyzing data on bone mineral density and body composition, the study seeks to identify potential risks associated with chemical exposure at critical life stages. Participants may provide urine samples to measure chemical exposure and undergo assessments of bone health.
Who could benefit from this research
Good fit: Ideal candidates for this research are women who are pregnant or in the perimenopausal stage.
Not a fit: Patients who are not pregnant or not in the perimenopausal stage may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for bone health issues in women during critical life stages.
How similar studies have performed: Previous studies have shown associations between chemical exposure and bone health, but this research aims to explore these effects in specific life stages, making it a novel approach.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Watkins, Deborah J — University of Michigan at Ann Arbor
- Study coordinator: Watkins, Deborah J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.