Investigating how exposure to certain chemicals affects infant reproductive development.
Phthalate and bisphenol exposure in relation to infant reproductive development during minipuberty
This study is looking at how certain chemicals found in baby products might affect the reproductive development of infants during their first six months of life, and it involves testing urine samples from mothers and measuring hormone levels and growth in their babies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11025036 on NIH RePORTER |
What this research studies
This research focuses on the critical period of minipuberty in infants, which occurs in the first six months of life when reproductive hormones are at their peak. It aims to understand how exposure to endocrine-disrupting chemicals, specifically phthalates and bisphenols found in common baby products, may impact reproductive development. The study will involve 480 full-term infants and will analyze urine samples from their mothers to assess both in utero and current chemical exposure, correlating these with hormone levels and anogenital distance in infants. This approach seeks to provide insights into how early chemical exposure could influence future reproductive health.
Who could benefit from this research
Good fit: Ideal candidates for this research are full-term infants whose mothers have participated in the study by providing urine samples during pregnancy.
Not a fit: Patients who are not infants or those who do not have mothers participating in the study will not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved guidelines for reducing harmful chemical exposure in infants, potentially enhancing their reproductive health.
How similar studies have performed: While previous studies have shown some associations between chemical exposure and reproductive hormones, this research is novel in its focus on anogenital distance during minipuberty.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Kahn, Linda G — New York University School of Medicine
- Study coordinator: Kahn, Linda G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.