Investigating how exposure to certain chemicals affects asthma risk in infants.
Official title: Associations between Perfluoroalkyl Substances (PFAS) Exposure and Aeroallergen Sensitization among Infants at High-Risk for Developing Asthma
Funded at Boston Children's Hospital · NIH-11001498 · Data updated 2026-11-12
This study is looking at how exposure to certain chemicals in the environment might affect babies who are more likely to develop asthma, with the goal of finding ways to help prevent asthma in young children.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $161,316 |
| NIH project number | 5K01HL171354-02 |
| Project ID | NIH-11001498 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are infants under the age of three who are at high risk for developing asthma, particularly those exposed to PFAS.
✕Less likely to help
Patients who are older than three years or those not at high risk for asthma may not benefit from this research.
What this research studies
This research focuses on understanding the impact of perfluoroalkyl substances (PFAS) exposure on infants who are at high risk for developing asthma. The study aims to explore how these environmental chemicals may influence the immune system and respiratory health in young children. By training a researcher in clinical trial design and advanced biostatistical methods, the project seeks to build a foundation for future studies that could lead to better prevention strategies for asthma in children. The research will involve collaboration with experts and the use of rigorous methodologies to gather and analyze data.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing asthma in infants exposed to harmful environmental chemicals.
How similar studies have gone: Previous research has indicated that early-life exposure to environmental chemicals can significantly impact respiratory health, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Boston Children's Hospital
Boston, United States Active
Researchers
- Principal investigator: Jackson-Browne, Medina Samira — Boston Children's Hospital
- Study coordinator: Jackson-Browne, Medina Samira
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.