NIH-funded research U01 cooperative agreement

Investigating how expecting mothers' diets affect children's food allergies

Official title: Expecting Mothers' Study of Consumption or Avoidance of Peanut and Egg (ESCAPE)

Funded at University of Rochester · NIH-10918323 · Data updated 2026-11-12

This study is looking at how eating or avoiding peanuts and eggs during pregnancy and breastfeeding might affect whether babies develop food allergies, especially for families with a history of allergies, to help find the best times to introduce these foods and reduce allergy risks.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Rochester
NIH-funded
Lab location1 site (Rochester, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$758,062
NIH project number5U01AI173032-02
Project IDNIH-10918323 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include expecting mothers, particularly those with a family history of food allergies or who are at higher risk of having allergic children.

Less likely to help

Patients who are not expecting or who do not have a family history of food allergies may not benefit from this research.

What this research studies

This research explores the impact of maternal consumption or avoidance of peanut and egg during pregnancy and breastfeeding on the development of food allergies in infants. It aims to identify critical periods for introducing allergenic foods to reduce the risk of allergies, particularly in high-risk populations. The study will involve monitoring dietary habits and allergy outcomes in infants, focusing on those with a family history of allergies. By analyzing these factors, the research seeks to provide insights into effective prevention strategies for food allergies.

Why it matters

Potential benefit: If successful, this research could lead to new guidelines for expecting mothers that may significantly reduce the incidence of food allergies in their children.

How similar studies have gone: Previous studies have shown mixed results regarding maternal diet and food allergy prevention, indicating that this research could provide valuable new insights.

Where this research is happening

  • University of Rochester
    Rochester, United States
    Active

Researchers

  • Principal investigator: Jarvinen-Seppo, Kirsi — University of Rochester
  • Study coordinator: Jarvinen-Seppo, Kirsi

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.