Investigating how exosomes influence tumor growth and spread in breast cancer
Official title: Exosome Secretion in Tumor Aggressiveness
Funded at Vanderbilt University · NIH-10978309 · Data updated 2026-11-12
This study is looking at tiny particles called exosomes that are released by cells and how they might help breast cancer grow and spread, with the goal of finding new ways to treat the disease and improve outcomes for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $200,877 |
| NIH project number | 1R50CA283661-01A1 |
| Project ID | NIH-10978309 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with breast cancer, particularly those with aggressive forms of the disease.
✕Less likely to help
Patients with non-cancerous conditions or those with early-stage breast cancer may not receive direct benefits from this research.
What this research studies
This research focuses on exosomes, which are tiny vesicles released by cells that play a significant role in cancer progression, particularly in breast cancer. The study aims to understand how these exosomes contribute to tumor aggressiveness and metastasis by carrying specific molecules that affect cancer cell behavior. Researchers will explore the mechanisms behind exosome production and their impact on the tumor microenvironment, using advanced imaging techniques to track these vesicles in action. By examining the relationship between exosome secretion and cancer cell migration, the research seeks to uncover potential therapeutic targets for improving patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating aggressive breast cancer by targeting exosome-related pathways.
How similar studies have gone: Previous research has shown promising results in understanding the role of exosomes in cancer, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
-
Vanderbilt University
Nashville, United States Active
Researchers
- Principal investigator: Sung, Bong Hwan — Vanderbilt University
- Study coordinator: Sung, Bong Hwan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.