Investigating how exosomes contribute to the progression of head and neck cancer
Exosomes in HNSCC Progression
This study is looking at tiny particles released by cancer cells in head and neck cancer to see how they help the cancer grow and spread, with the hope that the findings could lead to better treatments or ways to diagnose the disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project ID | NIH-11075132 on NIH RePORTER |
What this research studies
This research focuses on exosomes, which are tiny vesicles released by cancer cells that may play a significant role in the progression of head and neck squamous cell carcinoma (HNSCC). The study aims to understand how these exosomes, particularly those influenced by a protein called cortactin, contribute to cancer spread and the formation of new blood vessels. By examining the molecular contents of exosomes and their interactions with cancer cells, the researchers hope to uncover new insights into cancer behavior and potential therapeutic targets. Patients may benefit from findings that could lead to improved treatments or diagnostic tools based on exosomal biomarkers.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with head and neck squamous cell carcinoma, particularly those with aggressive disease characteristics.
Not a fit: Patients with other types of cancers or those without head and neck squamous cell carcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for diagnosing and treating head and neck cancer more effectively.
How similar studies have performed: Previous research has shown promising results in understanding the role of exosomes in cancer progression, suggesting that this approach could yield valuable insights.
Where this research is happening
Nashville, UNITED STATES
- Vanderbilt University — Nashville, United States (Active)
Researchers
- Principal investigator: Weaver, Alissa M — Vanderbilt University
- Study coordinator: Weaver, Alissa M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.