Investigating how exercise affects heart function and frailty in patients receiving stem cell transplants.

The Relationship of Exercise Associated Cardiac Reserve on Peak Oxygen Consumption and Frailty Measures in Individuals Undergoing Allogeneic Hematopoietic Stem Cell Transplant.

NIH-funded research Virginia Commonwealth University · NIH-11017762

This study is looking at how exercise ability relates to heart health in patients getting a special type of stem cell transplant, using safe MRI scans to measure how well they can use oxygen during exercise, with the goal of finding ways to help them feel better and recover faster.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVirginia Commonwealth University NIH-funded
Lab location1 site (Richmond, United States)
Project IDNIH-11017762 on NIH RePORTER

What this research studies

This research focuses on understanding the relationship between exercise capacity and heart function in patients undergoing allogeneic hematopoietic stem cell transplantation. Using advanced cardiovascular magnetic resonance imaging (MRI), the study aims to measure peak oxygen consumption, which is crucial for assessing overall health and recovery. The noninvasive approach eliminates risks associated with traditional imaging methods, making it safer for patients with compromised health. By collaborating with experts from various fields, the research seeks to identify factors that can improve exercise capacity and quality of life for these patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals undergoing allogeneic hematopoietic stem cell transplantation for hematologic malignancies.

Not a fit: Patients who are not undergoing stem cell transplantation or those with non-hematologic conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved exercise capacity and quality of life for patients undergoing stem cell transplants.

How similar studies have performed: Similar research has shown promise in using advanced imaging techniques to assess cardiac function in cancer patients, indicating potential for success in this novel approach.

Where this research is happening

Richmond, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions anti-cancer therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.