Investigating how exercise affects brain health in older adults with HIV
GPLD1: Association with Cognition and Amelioration through Exercise in Aging People with HIV
This study is looking at how a specific enzyme called GPLD1 relates to exercise and brain health in older adults living with HIV, and it aims to find out how staying active can help improve thinking skills and overall well-being, especially for those who might have trouble exercising.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10906758 on NIH RePORTER |
What this research studies
This research explores the role of a specific enzyme, GPLD1, in relation to physical activity and cognitive health in aging individuals living with HIV. It aims to understand how exercise can improve cognitive function and quality of life, especially for those facing physical limitations. By monitoring participants' physical activity through devices like Fitbits and accelerometers, the study will assess changes in GPLD1 levels and their association with various health markers. The goal is to identify alternative ways to achieve the cognitive benefits of exercise for those who may struggle to engage in physical activity due to health issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are aging individuals over 21 years old who are living with HIV and may have physical limitations that affect their ability to exercise.
Not a fit: Patients who are not living with HIV or those who do not have age-related cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new insights into improving cognitive health and quality of life for older adults living with HIV.
How similar studies have performed: Previous research has shown promising results in understanding the cognitive benefits of exercise in similar populations, suggesting that this approach may yield valuable insights.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Ellis, Ronald J. — University of California, San Diego
- Study coordinator: Ellis, Ronald J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.