Investigating how exercise affects brain health in older adults
Antioxidant Imaging Marker of Investigating Gains in Neurocognition in an Intervention Trial of Exercise (AIM-IGNITE)
['FUNDING_R01'] · UNIVERSITY OF KANSAS MEDICAL CENTER · NIH-10321247
This study is looking at how exercise can help improve brain health and thinking skills in older adults who might be at risk for Alzheimer's, and it's part of a bigger project that explores how lifestyle changes can boost brain function.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF KANSAS MEDICAL CENTER (nih funded) |
| Locations | 1 site (KANSAS CITY, UNITED STATES) |
| Trial ID | NIH-10321247 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the effects of exercise on cognitive function and brain health in older adults, particularly those at risk for Alzheimer's disease. It is part of a larger clinical trial called IGNITE, which examines how lifestyle changes can enhance neurocognition. Participants will undergo various assessments, including clinical evaluations and brain imaging, to explore the relationship between exercise, antioxidant levels in the brain, and cognitive performance. The study aims to clarify the mechanisms by which exercise may benefit brain health and identify potential new therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those aged 65 and above, who are interested in participating in an exercise program and may be at risk for cognitive decline.
Not a fit: Patients who are not elderly or those who do not have concerns about cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for maintaining cognitive function and brain health in older adults.
How similar studies have performed: Previous research has shown promising results regarding the benefits of exercise on cognitive function in older adults, indicating that this approach is both relevant and potentially impactful.
Where this research is happening
KANSAS CITY, UNITED STATES
- UNIVERSITY OF KANSAS MEDICAL CENTER — KANSAS CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEE, PHIL — UNIVERSITY OF KANSAS MEDICAL CENTER
- Study coordinator: LEE, PHIL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.