Investigating how excess glucose affects the small intestine and its potential treatment.
Official title: Numerical Experimentation of the Therapeutic Effect of Excess Glucose Transglycosylation and Optimization in the Proximal Small Intestine.
Funded at Prairie View Agri & Mech University · NIH-10936219 · Data updated 2026-11-12
This study is looking at how too much sugar in our diet can cause problems like non-alcoholic fatty liver disease, and it aims to find better ways to help people manage their sugar intake for improved health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Prairie View Agri & Mech University NIH-funded |
| Lab location | 1 site (Prairie View, UNITED STATES) |
| Project start | August 1, 2024 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $175,935 |
| NIH project number | 1R16GM154691-01 |
| Project ID | NIH-10936219 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with adult-onset diabetes mellitus or those at risk of developing metabolic disorders due to high sugar intake.
✕Less likely to help
Patients who do not consume high levels of sugar or have no metabolic disorders may not benefit from this research.
What this research studies
This research focuses on understanding how excess glucose and fructose in the gastrointestinal system can lead to health issues, particularly non-alcoholic fatty liver disease (NAFLD). By examining the dynamics of glucose in the proximal small intestine, the study aims to find ways to optimize and remediate the effects of these sugars. The approach involves using glucose as a model to explore how to better manage and process these nutrients in the body, potentially improving overall health outcomes for individuals with high sugar diets.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing excess glucose in patients, potentially reducing the risk of related diseases.
How similar studies have gone: While the specific approach of optimizing glucose remediation in the proximal small intestine is novel, related research has shown promise in understanding the impacts of sugar metabolism on health.
Where this research is happening
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Prairie View Agri & Mech University
Prairie View, United States Active
Researchers
- Principal investigator: Olanrewaju, Kazeem — Prairie View Agri & Mech University
- Study coordinator: Olanrewaju, Kazeem
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.