Investigating how ethnicity affects blood tests for Alzheimer's detection
Ethnoracial Impact on Blood-Based Biomarker Detection of Alzheimer's in Primary Care Patients
This study is looking at how differences in race and ethnicity, especially for African Americans, can affect the way we find early signs of Alzheimer's disease using blood tests, with the goal of making these tests easier and cheaper for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-11051892 on NIH RePORTER |
What this research studies
This research focuses on understanding how ethnic and racial differences, particularly among African Americans, impact the detection of Alzheimer's disease through blood-based biomarkers. The study aims to develop less invasive and cost-effective methods to identify early stages of Alzheimer's, which is crucial as the number of affected individuals is expected to rise significantly. By examining the potential of various exosomes in blood samples, the research seeks to validate their effectiveness in predicting the progression from mild cognitive impairment to Alzheimer's disease. This approach will help address the existing disparities in Alzheimer's diagnosis and treatment among different ethnic groups.
Who could benefit from this research
Good fit: Ideal candidates for this research include African American individuals who are at risk for or have been diagnosed with mild cognitive impairment.
Not a fit: Patients who do not identify as African American or those who are not at risk for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and treatment strategies for Alzheimer's disease, particularly for African American patients.
How similar studies have performed: Other research has shown promise in using blood-based biomarkers for Alzheimer's detection, but this specific focus on ethnic disparities is relatively novel.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Winston, Charisse N — University of Southern California
- Study coordinator: Winston, Charisse N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.