NIH-funded research R01 grant

Investigating how environmental pollutants affect heart health

Official title: Identifying environmental pollutants detrimental to the cardiovascular system

Funded at Boston University Medical Campus · NIH-11072681 · Data updated 2026-11-12

This study is looking at how certain harmful chemicals in the environment can affect your heart and blood vessels, especially if they build up in your body, and it's for anyone interested in understanding how pollution might impact heart health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston University Medical Campus
NIH-funded
Lab location1 site (Boston, United States)
Project startJanuary 1, 2025
Project endNovember 30, 2028
Funding year2025
Award (this year)$705,279
NIH project number1R01HL173978-01A1
Project IDNIH-11072681 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with a history of exposure to environmental pollutants or those with cardiovascular conditions.

Less likely to help

Patients who have no history of exposure to environmental pollutants or do not have cardiovascular health concerns may not benefit from this research.

What this research studies

This research explores the harmful effects of persistent organic pollutants (POPs) on the cardiovascular system. It focuses on how these pollutants, which accumulate in human fat tissues, can lead to vascular dysfunction and inflammation, potentially causing heart disease. The study employs a variety of advanced techniques, including cellular imaging and RNA sequencing, to understand the mechanisms by which these toxicants disrupt normal vascular function. By examining both direct and indirect effects on blood vessel health, the research aims to uncover critical insights into how environmental factors contribute to cardiovascular issues.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention of cardiovascular diseases linked to environmental pollutants.

How similar studies have gone: Previous research has indicated that environmental pollutants can negatively impact cardiovascular health, suggesting that this investigation builds on established findings.

Where this research is happening

  • Boston University Medical Campus
    Boston, United States
    Active

Researchers

  • Principal investigator: Gokce, Noyan — Boston University Medical Campus
  • Study coordinator: Gokce, Noyan

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.