Investigating how environmental factors and genetics affect asthma in African American children
Epigenome-wide variations and socio-environmental exposures in African American asthmatic children
This study is looking at how genetics and the environment affect asthma in African American kids, with the goal of finding better ways to predict and manage their asthma.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-10877046 on NIH RePORTER |
What this research studies
This research focuses on understanding the complex relationship between genetic factors and socio-environmental exposures that contribute to asthma in African American children. By utilizing advanced geocoding algorithms and statistical methods, the study aims to integrate various data types, including environmental, clinical, and genetic information, to create a comprehensive asthma risk prediction model. The research will analyze epigenetic data from a well-characterized cohort of African American pediatric asthma patients to identify specific risk factors and improve asthma management strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American children aged 0-11 years who have been diagnosed with asthma.
Not a fit: Patients who do not have asthma or are outside the age range of 0-11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate asthma risk assessments and tailored interventions for African American children, ultimately improving their health outcomes.
How similar studies have performed: Previous research has shown promising results in using genetic and environmental data to understand asthma disparities, indicating that this approach has potential for success.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Mersha, Tesfaye B. — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Mersha, Tesfaye B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.